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Biomedical Engineering

Overview
Domain Expertise
  • Riverside Research engages in advanced research and technology development that historically has applied ultrasound to biomedical problems related to detection, diagnosis, imaging, and treatment of disease. Recently, the laboratory has added exciting new optical capabilities that synergize with acoustics to achieve these same purposes in novel and effective ways. Clinical studies have included ophthalmic diagnosis and therapy, liver and kidney diagnosis, thrombus and plaque characterization, prostate-cancer imaging, and detection of lymph-node metastases. Related ultrasonic technology studies have included therapeutic transducer and bioeffects modeling, and novel transducer-fabrication methods. Developing optics technologies include fine-resolution, functional as well as structural, all-optical, holographic, and photoacoustic imaging. Potential clinical applications include non-contact assessment of burns and wounds, evaluation of incipient pressure ulcers, and early detection of ophthalmic disease. The methods being investigated by the laboratory are also applicable to materials testing and a wide range of other non-biomedical topics.

    • Characterization and imaging of biological tissue and non-biological materials based on quantitative-ultrasound technology
    • Integration of acoustical and optical imaging technologies, e.g., functional and structural imaging using photoacoustics
    • Ultrasonic bioeffects, safety, and therapy
    • Ultrasound transducer technology including fabrication of novel ultrasound transducers and sensors using piezoelectric polymer films
    • Acoustical and optical scattering theory and modeling

Equipment/Toolsets

  • Acoustic benches adaptable to a broad range of experiments involving computer-controlled, high-frequency, pulse-echo, ultrasonic scanning and echo-signal acquisition or requiring delivery of high-intensity, focused ultrasound
  • Ultrasound beam-profiling, pulse-characterization, and acoustic-field measurements with calibrated hydrophones
  • Piezopolymer transducer-fabrication facility, including fabrication of annular and linear-array transducer configurations
  • Multiple optical benches adaptable to a broad range of experiments necessitating high spatial or temporal coherence at a variety of different wavelengths and pulse properties, including modulated, continuous-wave illumination
  • Acoustic characterization of scattering by homogeneous or heterogeneous materials
  • Computer-controlled, high-precision, 3D, machining capability
  • Integrated acoustical and optical data-acquisition systems
  • Signal and image analysis with emphasis on 2D and 3D acoustical and optical data
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